IgA Nephropathy

To fully grasp the concept of this condition, you must first understand how kidneys work. The kidneys, as we all know, are two bean-shaped organs placed right below the rib cage. The major function of the kidneys is to filter blood and remove waste elements from the body such as creatinine and urea.

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What is IgA Nephropathy?

IgA nephropathy (Berger's disease): It is a chronic kidney illness caused by an antibody called immunoglobulin A (IgA) that accumulates in your kidneys. It normally advances slowly and has an impact on renal function. Because it is a long process, many people miss the symptoms. Continue reading to discover about the disease's symptoms, causes, and treatment options.

Symptoms of IgA nephropathy

It is a long procedure with no visible symptoms. The main sign of this condition is blood in the urine, which is also known as "Hematuria."

Signs and symptoms are:

  • Brown or tea-colored urine
  • Pain on the side of your back
  • Protein in the urine (proteinuria)
  • High blood pressure (hypertension)
  • Swelling of the hands and feet
Causes of IgA nephropathy

To fight dangerous germs and viruses, the immune system relies on a large protein called immunoglobulin or antibodies. Immunoglobulin A, or IgA, is a kind of immunoglobulin. When a person develops IgA nephropathy, their IgA does not work properly. Instead of solely sticking to bacteria and viruses, IgA improperly attaches to other IgA molecules, forming long chains.

As the chains pass through the blood, they eventually end up deposited in the kidney's filters. (glomeruli). These IgA crystals promote inflammation in the body. This infection has the potential to cause kidney damage.

It is still unknown why a person's IgA reacts in this manner. Researchers believe the illness has a hereditary component because it occasionally happens in families.

According to studies, the cause of IgA accumulation is unknown, but several factors are linked to the illness, such as:

  • Genes: IgA is a genetic ailment, and those who have a family history of it are more likely to have it themselves.
  • Infections: People who have HIV or other bacterial infections are more likely to develop IgA nephropathy.
  • Cirrhosis, a condition in which healthy liver tissue is replaced by scar tissue, and chronic hepatitis B and C infection are examples of liver illnesses. This can also lead to IgA Nephropathy.
  • Ethnicity: White and Asian ethnic groups are more prone to acquire IgA nephropathy than Blacks and persons of other races.
  • Age: People in their late teens to late thirties are the most likely to get affected.
Diagnosis of IgA nephropathy

When red blood cells and protein are discovered in the urine during routine testing, this could be the first indicator of IgA nephropathy.

A medical practitioner will evaluate you physically and inquire about your medical and family history. They may also inquire about your symptoms if you have ever noticed that your urine is black or crimson in color, or if you have a history of urinary tract infections. (UTIs).

The following tests may also be performed to help confirm a diagnosis and distinguish your sickness from other diseases:

  • eGFR test to assess kidney function
  • A creatinine and urea test to see whether waste products are accumulating in the body
  • A renal tissue examination to check for IgA deposits (a biopsy is required to establish a diagnosis)
  • Blood pressure measurement
  • Test for sugar and cholesterol
Treatment of IgA nephropathy

Managing Blood Pressure

High blood pressure, often known as hypertension, is a common problem. It can cause serious health problems even in the absence of symptoms. One of the best strategies to solve numerous issues is to manage high blood pressure.

Tips for natural control Low BP:

  • Consistent Physical Activity.
  • Eat less salt, drink less alcohol, and calm down if you're stressed.

Controlling Blood Sugar Levels

High blood sugar, sometimes referred to as hyperglycemia, is linked to diabetes and can impair kidney function.

Natural strategies/tips for regulating blood sugar:

Exercise frequently, manage your carbohydrate consumption, eat more fiber, remain hydrated, and use portion control.